A Case of Follicular Tumor of Uncertain Malignant Potential (FT-UMP) with Glomeruloid Features Showing Capsular Mucinous Degeneration.

The most recent revision of the World Health Organization (WHO) Classification of Tumours of Endocrine Organs introduced a new variant of follicular thyroid carcinoma (FTC). It is characterized by a "glomeruloid" architectural pattern of growth. We present a case of follicular tumor with glomeruloid features, with Alcian Blue positive mucinous stromal degeneration in foci of questionable capsular microinvasion. At our knowledge, this the second case of glomeruloid follicular tumor in the literature and the first case in which Alcian Blue staining was used to investigate capsular invasion. Moreover, RAS mutation further supports that this is a variant of follicular tumor with uncertain malignant potential.

Giant pseudocyst of the abdominal wall following incisional ventral hernia repair: an extremely rare clinical entity. Report of a case.

BACKGROUND: The gold standard treatment for incisional ventral hernia (IVH) is a surgical repair with mesh employment, nevertheless this procedure is burdened by several post-operative complications; among these latter, giant pseudocyst of abdominal wall (GPAW) formation is one of the most rare and its etiopathogenesis remains unclear. CASE REPORT: We describe the case report of a 36 years old, diabetic and obese woman, previously underwent to a csection and IVH repair with on-lay mesh placement, presented to our unit with an asymptomatic left iliac fossa swelling. At ultrasound (US) and CT scan examination it appears to be a subcutaneous cyst of the anterior abdominal wall associated with a recurrent IVH. Therefore, she underwent to a surgical procedure in order to accomplish a complete excision of the lesion along with a repair of the incisional IVH, with a sub-lay mesh positioning. The extensive dead space resulting from the procedure was managed with a quilting suture. No recurrence or complications have been detected at 2 years follow up. CONCLUSION: GPAWs are a rare clinical entity following IVH repair, which occur commonly in female obese patients treated with on-lay mesh positioning. The only effective and definitive treatment is a complete surgical excision along with a correct management of the dead space resulting from the surgical procedure, in order to reduce the recurrence rate. KEY WORDS: Abdominal wall, Incisional hernia, Mesh, Pseudocyst, Surgery.